International Journals
2021
2020
- 48. "Finely-Tuned Calcium Oscillations in Osteoclast Differentiation and Bone Resorption"
Hiroyuki Okada, Koji Okabe, Sakae Tanaka
International Journal of Molecular Sciences 22, 180 (2020).
- 47. "ChIP-Seq Assays from Mammalian Cartilage and Chondrocytes."
Akira Yamakawa, Hironori Hojo, Shinsuke Ohba
Methods in molecular biology (Clifton, N.J.) 2245, 167 (2020).
- 46. "Gene regulatory landscape in osteoblast differentiation."
Hironori Hojo, Shinsuke Ohba
Bone 137, 115458 (2020).
- 45. "Understanding paraxial mesoderm development and sclerotome specification for skeletal repair."
Shoichiro Tani, Ung-Il Chung, Shinsuke Ohba, Hironori Hojo
Experimental & molecular medicine 52, 1166 (2020).
- 44. "Hedgehog Activation Regulates Human Osteoblastogenesis."
Shoko Onodera, Akiko Saito, Hironori Hojo, Takashi Nakamura, Denise Zujur, Katsuhito Watanabe, Nana Morita, Daigo Hasegawa, Hideki Masaki, Hiromitsu Nakauchi, Takeshi Nomura, Takahiko Shibahara, Akira Yamaguchi, Ung-Il Chung, Toshifumi Azuma, Shinsuke Ohba
Stem cell reports 15, 125 (2020).
- 43. "Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers."
Denise Zujur, Kosuke Kanke, Shoko Onodera, Shoichiro Tani, Jenny Lai, Toshifumi Azuma, Xiaonan Xin, Alexander C Lichtler, David W Rowe, Taku Saito, Sakae Tanaka, Hideki Masaki, Hiromitsu Nakauchi, Ung-Il Chung, Hironori Hojo, Shinsuke Ohba
Regenerative therapy 14, 19 (2020).
- 42. "Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis."
Qing Jiang, Xin Qin, Carolina Andrea Yoshida, Hisato Komori, Kei Yamana, Shinsuke Ohba, Hironori Hojo, Brad St Croix, Viviane K S Kawata-Matsuura, Toshihisa Komori
International journal of molecular sciences 21, null (2020).
2019
- 41. "Insights into Gene Regulatory Networks in Chondrocytes."
Hironori Hojo, Shinsuke Ohba
International journal of molecular sciences 20, 6324 (2019).
- 40. "Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone."
Fengjun Xuan, Fumiko Yano, Daisuke Mori, Ryota Chijimatsu, Yuji Maenohara, Hideki Nakamoto, Yoshifumi Mori, Yuma Makii, Takeshi Oichi, Makoto Mark Taketo, Hironori Hojo, Shinsuke Ohba, Ung-Il Chung, Sakae Tanaka, Taku Saito
Arthritis research & therapy 21, 247 (2019).
- 39. "Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds."
Manabu Kawata, Daisuke Mori, Kosuke Kanke, Hironori Hojo, Shinsuke Ohba, Ung-Il Chung, Fumiko Yano, Hideki Masaki, Makoto Otsu, Hiromitsu Nakauchi, Sakae Tanaka, Taku Saito
Stem cell reports 13, 530 (2019).
2018
- 38. "A report of the 17th congress of the Japanese Society for Regenerative Medicine."
Shinsuke Ohba, Hironori Hojo, Ung-Il Chung
Regenerative therapy 9, 10 (2018).
- 37. "Generation of orthotopically functional salivary gland from embryonic stem cells."
Junichi Tanaka, Miho Ogawa, Hironori Hojo, Yusuke Kawashima, Yo Mabuchi, Kenji Hata, Shiro Nakamura, Rika Yasuhara, Koki Takamatsu, Tarou Irié, Toshiyuki Fukada, Takayoshi Sakai, Tomio Inoue, Riko Nishimura, Osamu Ohara, Ichiro Saito, Shinsuke Ohba, Takashi Tsuji, Kenji Mishima
Nature communications 9, 4216 (2018).
- 36. "Bone regeneration by human dental pulp stem cells using a helioxanthin derivative and cell-sheet technology."
Yasuyuki Fujii, Yoko Kawase-Koga, Hironori Hojo, Fumiko Yano, Marika Sato, Ung-Il Chung, Shinsuke Ohba, Daichi Chikazu
Stem cell research & therapy 9, 24 (2018).
2017
- 35. "Identification of the gene-regulatory landscape in skeletal development and potential links to skeletal regeneration."
Hironori Hojo, Ung-Il Chung, Shinsuke Ohba
Regenerative therapy 6, 100 (2017).
- 34. "Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions."
Denise Zujur, Kosuke Kanke, Alexander C Lichtler, Hironori Hojo, Ung-Il Chung, Shinsuke Ohba
Science advances 3, e1602875 (2017).
- 33. "Repair of segmental radial defects in dogs using tailor-made titanium mesh cages with plates combined with calcium phosphate granules and basic fibroblast growth factor-binding ion complex gel."
Muneki Honnami, Sungjin Choi, I-Li Liu, Wataru Kamimura, Tetsushi Taguchi, Makoto Ichimura, Yukinori Urushisaki, Hironori Hojo, Nobuyuki Shimohata, Shinsuke Ohba, Koichi Amaya, Hiroyuki Koyama, Ryohei Nishimura, Ung-Il Chung, Nobuo Sasaki, Manabu Mochizuki
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 20, 91 (2017).
2016
- 32. "An Emerging Regulatory Landscape for Skeletal Development."
Hironori Hojo, Andrew P McMahon, Shinsuke Ohba
Trends in genetics : TIG 32, 774 (2016).
- 31. "Local administration of a hedgehog agonist accelerates fracture healing in a mouse model."
Miki Kashiwagi, Hironori Hojo, Yoshiaki Kitaura, Yujiro Maeda, Hailati Aini, Tsuyoshi Takato, Ung-Il Chung, Shinsuke Ohba
Biochemical and biophysical research communications 479, 772 (2016).
- 30. "AP-1 family members act with Sox9 to promote chondrocyte hypertrophy."
Xinjun He, Shinsuke Ohba, Hironori Hojo, Andrew P McMahon
Development (Cambridge, England) 143, 3012 (2016).
- 29. "Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification."
Hironori Hojo, Shinsuke Ohba, Xinjun He, Lick Pui Lai, Andrew P McMahon
Developmental cell 37, 238 (2016).
2015
- 28. "Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte"
Shinsuke Ohba, Xinjun He, Hironori Hojo, Andrew P. McMahon
CELL REPORTS 12, 229 (2015).
- 27. "Signaling pathways regulating the specification and differentiation of the osteoblast lineage."
Hironori Hojo, Shinsuke Ohba, Ung-Il Chung
Regenerative therapy 1, 57 (2015).
2014
- 26. "Gli1 Haploinsufficiency Leads to Decreased Bone Mass with an Uncoupling of Bone Metabolism in Adult Mice"
Yoshiaki Kitaura, Hironori Hojo, Yuske Komiyama, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba
PLOS ONE 9, e109597 (2014).
- 25. "Bone Regeneration by the Combined Use of Tetrapod-Shaped Calcium Phosphate Granules with Basic Fibroblast Growth Factor-Binding Ion Complex Gel in Canine Segmental Radial Defects"
Muneki Honnami, Sungjin Choi, I-li Liu, Wataru Kamimura, Tetsushi Taguchi, Hironori Hojo, Nobuyuki Shimohata, Shinsuke Ohba, Hiroyuki Koyama, Ryohei Nishimura, Ung-il Chung, Nobuo Sasaki, Manabu Mochizuki
JOURNAL OF VETERINARY MEDICAL SCIENCE 76, 955 (2014).
- 24. "Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions"
Kosuke Kanke, Hideki Masaki, Taku Saito, Yuske Komiyama, Hironori Hojo, Hiromitsu Nakauchi, Alexander C. Lichtler, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba
STEM CELL REPORTS 2, 751 (2014).
2013
- 23. "Repair of rabbit segmental femoral defects by using a combination of tetrapod-shaped calcium phosphate granules and basic fibroblast growth factor-binding ion complex gel"
Muneki Honnami, Sungjin Choi, I-li Liu, Wataru Kamimura, Tetsushi Taguchi, Hironori Hojo, Nobuyuki Shimohata, Shinsuke Ohba, Hiroyuki Koyama, Ryohei Nishimura, Ung-il Chung, Nobuo Sasaki, Manabu Mochizuki
BIOMATERIALS 34, 9056 (2013).
- 22. "Generation of Col2a1-EGFP iPS Cells for Monitoring Chondrogenic Differentiation"
Taku Saito, Fumiko Yano, Daisuke Mori, Shinsuke Ohba, Hironori Hojo, Makoto Otsu, Koji Eto, Hiromitsu Nakauchi, Sakae Tanaka, Ung-il Chung, Hiroshi Kawaguchi
PLOS ONE 8, e74137 (2013).
- 21. "Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis"
Horacio Cabral, Mami Murakami, Hironori Hojo, Yasuko Terada, Mitsunobu R. Kano, Ung-Il Chung, Nobuhiro Nishiyama, Kazunori Kataoka
Proceedings of the National Academy of Sciences of the United States of America 110, 11397 (2013).
- 20. "Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration"
Fumiko Yano, Hironori Hojo, Shinsuke Ohba, Taku Saito, Muneki Honnami, Manabu Mochizuki, Tsuyoshi Takato, Hiroshi Kawaguchi, Ung-Il Chung
BIOMATERIALS 34, 5581 (2013).
- 19. "Bone healing by sterilizable calcium phosphate tetrapods eluting osteogenic molecules"
Yujiro Maeda, Hironori Hojo, Nobuyuki Shimohata, Sungjin Choi, Kenichi Yamamoto, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba
BIOMATERIALS 34, 5530 (2013).
- 18. "A novel disease-modifying osteoarthritis drug candidate targeting Runx1"
Fumiko Yano, Hironori Hojo, Shinsuke Ohba, Atsushi Fukai, Yoko Hosaka, Toshiyuki Ikeda, Taku Saito, Makoto Hirata, Hirotaka Chikuda, Tsuyoshi Takato, Hiroshi Kawaguchi, Ung-il Chung
ANNALS OF THE RHEUMATIC DISEASES 72, 748 (2013).
- 17. "Tenomodulin Expression in the Periodontal Ligament Enhances Cellular Adhesion"
Yuske Komiyama, Shinsuke Ohba, Nobuyuki Shimohata, Keiji Nakajima, Hironori Hojo, Fumiko Yano, Tsuyoshi Takato, Denitsa Docheva, Chisa Shukunami, Yuji Hiraki, Ung-il Chung
PLOS ONE 8, e60203 (2013).
- 16. "Hedgehog-Gli Activators Direct Osteo-chondrogenic Function of Bone Morphogenetic Protein toward Osteogenesis in the Perichondrium"
Hironori Hojo, Shinsuke Ohba, Kiyomi Taniguchi, Masataka Shirai, Fumiko Yano, Taku Saito, Toshiyuki Ikeda, Keiji Nakajima, Yuske Komiyama, Naomi Nakagata, Kentaro Suzuki, Yuji Mishina, Masahisa Yamada, Tomohiro Konno, Tsuyoshi Takato, Hiroshi Kawaguchi, Hideki Kambara, Ung-il Chung
JOURNAL OF BIOLOGICAL CHEMISTRY 288, 9924 (2013).
2012
- 15. "Famotidine suppresses osteogenic differentiation of tendon cells in vitro and pathological calcification of tendon in vivo"
Kenichi Yamamoto, Hironori Hojo, Isao Koshima, Ung-il Chung, Shinsuke Ohba
JOURNAL OF ORTHOPAEDIC RESEARCH 30, 1958 (2012).
- 14. "Bioactive factors for tissue regeneration: state of the art."
Shinsuke Ohba, Hironori Hojo, Ung-Il Chung
Muscles, ligaments and tendons journal 2, 193 (2012).
- 13. "Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification"
Hironori Hojo, Shinsuke Ohba, Fumiko Yano, Taku Saito, Toshiyuki Ikeda, Keiji Nakajima, Yuske Komiyama, Naomi Nakagata, Kentaro Suzuki, Tsuyoshi Takato, Hiroshi Kawaguchi, Ung-il Chung
JOURNAL OF BIOLOGICAL CHEMISTRY 287, 17860 (2012).
- 12. "Current progress on tissue engineering of bone and cartilage."
Ohba S, Hojo H, Chung UI
Endocrinology and metabolism 27, 1 (2012).
2011
- 11. "Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling"
Takayuki Yonezawa, Ji-Won Lee, Ayaka Hibino, Midori Asai, Hironori Hojo, Byung-Yoon Cha, Toshiaki Teruya, Kazuo Nagai, Ung-Il Chung, Kazumi Yagasaki, Je-Tae Woo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 409, 260 (2011).
2010
- 10. "Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system"
Hironori Hojo, Fumiko Yano, Shinsuke Ohba, Kazuyo Igawa, Keiji Nakajima, Yuske Komiyama, Akinori Kan, Toshiyuki Ikeda, Takayuki Yonezawa, Je-Tae Woo, Tsuyoshi Takato, Kozo Nakamura, Hiroshi Kawaguchi, Ung-il Chung
JOURNAL OF BONE AND MINERAL METABOLISM 28, 627 (2010).
- 9. "Coordination of chondrogenesis and osteogenesis by hypertrophic chondrocytes in endochondral bone development"
Hironori Hojo, Shinsuke Ohba, Fumiko Yano, Ung-il Chung
JOURNAL OF BONE AND MINERAL METABOLISM 28, 489 (2010).
- 8. "Erratum to Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative [Biochem. Biophys. Res. Commun. (2010), 395, 502-508]"
Keiji Nakajima, Yusuke Komiyama, Hironori Hojo, Shinsuke Ohba, Fumiko Yano, Naoko Nishikawa, Sigeo Ihara, Hiroyuki Aburatani, Tsuyoshi Takato, Ung-il Chung
Biochemical and Biophysical Research Communications 397, 631 (2010).
- 7. "Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative"
Keiji Nakajima, Yusuke Komiyama, Hironori Hojo, Shinsuke Ohba, Fumiko Yano, Naoko Nishikawa, Hiroyuki Aburatani, Tsuyoshi Takato, Ung-il Chung
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 395, 502 (2010).
2009
- 6. "Screening of Chondrogenic Factors With a Real-Time Fluorescence-Monitoring Cell Line ATDC5-C2ER Identification of Sorting Nexin 19 as a Novel Factor"
Akinori Kan, Toshiyuki Ikeda, Taku Saito, Fumiko Yano, Atushi Fukai, Hironori Hojo, Toru Ogasawara, Naoshi Ogata, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguchi
ARTHRITIS AND RHEUMATISM 60, 3314 (2009).
- 5. "Interference by adrenaline with chondrogenic differentiation through suppression of gene transactivation mediated by Sox9 family members"
Takeshi Takarada, Hironori Hojo, Mika Iemata, Koichi Sahara, Ayumi Kodama, Nobuhiro Nakamura, Eiichi Hinoi, Yukio Yoneda
BONE 45, 568 (2009).
2008
- 4. "Development of high-throughput screening system for osteogenic drugs using a cell-based sensor"
Hironori Hojo, Kazuyo Igawa, Shinsuke Ohba, Fumiko Yano, Keiji Nakajima, Yuske Komiyama, Toshiyuki Ikeda, Alexander C. Lichtler, Je-Tae Woo, Takayuki Yonezawa, Tsuyoshi Takato, Ung-il Chung
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 376, 375 (2008).
-2007
- 3. "Up-regulation of per mRNA expression by parathyroid hormone through a protein kinase A-CREB-dependent mechanism in chondrocytes"
Eiichi Hinoi, Taichi Ueshima, Hironori Hojo, Mika Iemata, Takeshi Takarada, Yukio Yoneda
JOURNAL OF BIOLOGICAL CHEMISTRY 281, 23632 (2006).
- 2. "Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation"
E Hinoi, S Fujimori, LY Wang, H Hojo, K Uno, Y Yoneda
JOURNAL OF BIOLOGICAL CHEMISTRY 281, 18015 (2006).
- 1. "Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis"
E Hinoi, R Ohashi, S Miyata, Y Kato, M Iemata, H Hojo, T Takarada, Y Yoneda
BIOCHEMICAL PHARMACOLOGY 70, 1744 (2005).
和文原著
- 1. "[Novel small compound in combination with cell-sheet technology for articular cartilage regeneration]."
Yano F, Hojo H, Chung Ui
Clinical calcium 21, 871 (2011).
